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A mutually exclusive stem–loop arrangement in roX2 RNA is essential for X-chromosome regulation in Drosophila

The X chromosome provides an ideal model system to study the contribution of RNA–protein interactions in epigenetic regulation. In male flies, roX long noncoding RNAs (lncRNAs) harbor several redundant domains to interact with the ubiquitin ligase male-specific lethal 2 (MSL2) and the RNA helicase M...

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Detalles Bibliográficos
Autores principales: Ilik, Ibrahim Avsar, Maticzka, Daniel, Georgiev, Plamen, Gutierrez, Noel Marie, Backofen, Rolf, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710142/
https://www.ncbi.nlm.nih.gov/pubmed/29066499
http://dx.doi.org/10.1101/gad.304600.117