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Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila

Regulatory decisions in Drosophila require Polycomb group (PcG) proteins to maintain the silent state and Trithorax group (TrxG) proteins to oppose silencing. Since PcG and TrxG are ubiquitous and lack apparent sequence specificity, a long-standing model is that targeting occurs via protein interact...

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Detalles Bibliográficos
Autores principales: Kang, Hyuckjoon, Jung, Youngsook L., McElroy, Kyle A., Zee, Barry M., Wallace, Heather A., Woolnough, Jessica L., Park, Peter J., Kuroda, Mitzi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710143/
https://www.ncbi.nlm.nih.gov/pubmed/29070704
http://dx.doi.org/10.1101/gad.305987.117