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Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells
The Lin28/let-7 axis plays an important role in tumor initiation and developmental processes. Lin28B is upregulated in a variety of cancers, and its overexpression enhances cancer cell proliferation and radioresistance through the suppression of let-7 micro RNA expression. In this study, we investig...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710593/ https://www.ncbi.nlm.nih.gov/pubmed/28482074 http://dx.doi.org/10.1093/jrr/rrx022 |