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Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells

The Lin28/let-7 axis plays an important role in tumor initiation and developmental processes. Lin28B is upregulated in a variety of cancers, and its overexpression enhances cancer cell proliferation and radioresistance through the suppression of let-7 micro RNA expression. In this study, we investig...

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Detalles Bibliográficos
Autores principales:	Park, Seong-Joon, Heo, Kyu, Choi, Chulwon, Yang, Kwangmo, Adachi, Akiko, Okada, Hiroko, Yoshida, Yukari, Ohno, Tatsuya, Nakano, Takashi, Takahashi, Akihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710593/ https://www.ncbi.nlm.nih.gov/pubmed/28482074 http://dx.doi.org/10.1093/jrr/rrx022

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