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Aquaporin 0 Modulates Lens Gap Junctions in the Presence of Lens-Specific Beaded Filament Proteins

PURPOSE: The objective of this study was to understand the molecular and physiologic mechanisms behind the lens cataract differences in Aquaporin 0-knockout-Heterozygous (AQP0-Htz) mice developed in C57 and FVB (lacks beaded filaments [BFs]) strains. METHODS: Lens transparency was studied using dark...

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Detalles Bibliográficos
Autores principales: Kumari, Sindhu, Gao, Junyuan, Mathias, Richard T., Sun, Xiurong, Eswaramoorthy, Amizhdini, Browne, Nicholas, Zhang, Nigel, Varadaraj, Kulandaiappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710632/
https://www.ncbi.nlm.nih.gov/pubmed/29196765
http://dx.doi.org/10.1167/iovs.17-22153