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The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance

In β cells, stimulation by metabolic, hormonal, neuronal, and pharmacological factors is coupled to secretion of insulin through different intracellular signaling pathways. Our knowledge about the molecular machinery supporting these pathways and the patterns of signals it generates comes mostly fro...

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Detalles Bibliográficos
Autores principales: Skelin Klemen, Maša, Dolenšek, Jurij, Slak Rupnik, Marjan, Stožer, Andraž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710702/
https://www.ncbi.nlm.nih.gov/pubmed/28662366
http://dx.doi.org/10.1080/19382014.2017.1342022