Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit

Several ribosomal proteins (RPs) in response to various ribosomal stressors have been shown to play a critical role in p53-dependent regulation of cell cycle arrest, apoptosis and tumor suppression. Here, we report ribosomal protein L22 (RPL22/eL22) as a novel p53 activator highly mutated (mostly de...

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Detalles Bibliográficos
Autores principales: Cao, Bo, Fang, Ziling, Liao, Peng, Zhou, Xiang, Xiong, Jianping, Zeng, Shelya, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710875/
https://www.ncbi.nlm.nih.gov/pubmed/29207594
http://dx.doi.org/10.18632/oncotarget.21544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710875/
https://www.ncbi.nlm.nih.gov/pubmed/29207594
http://dx.doi.org/10.18632/oncotarget.21544

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