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Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit
Several ribosomal proteins (RPs) in response to various ribosomal stressors have been shown to play a critical role in p53-dependent regulation of cell cycle arrest, apoptosis and tumor suppression. Here, we report ribosomal protein L22 (RPL22/eL22) as a novel p53 activator highly mutated (mostly de...
Autores principales: | Cao, Bo, Fang, Ziling, Liao, Peng, Zhou, Xiang, Xiong, Jianping, Zeng, Shelya, Lu, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710875/ https://www.ncbi.nlm.nih.gov/pubmed/29207594 http://dx.doi.org/10.18632/oncotarget.21544 |
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