UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation

Understanding protein subcellular localization is important to determining the functional role of specific proteins. T-cell protein tyrosine phosphatase (TC-PTP) contains bipartite nuclear localization signals (NLSI and NLSII) in its C-terminus. We previously have demonstrated that the nuclear form...

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Detalles Bibliográficos
Autores principales: Kim, Mihwa, Morales, Liza D., Baek, Minwoo, Slaga, Thomas J., DiGiovanni, John, Kim, Dae Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710877/
https://www.ncbi.nlm.nih.gov/pubmed/29207596
http://dx.doi.org/10.18632/oncotarget.21794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710877/
https://www.ncbi.nlm.nih.gov/pubmed/29207596
http://dx.doi.org/10.18632/oncotarget.21794

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