Combination therapy with an OX40L fusion protein and a vaccine targeting the transcription factor twist inhibits metastasis in a murine model of breast cancer

OX40 is a costimulatory receptor that potentiates proliferation, survival, memory formation, and effector function of CD4(+) and CD8(+) T-cells, while overcoming the suppressive activity of regulatory T-cells (Tregs). Here, we explored the combination of an OX40L fusion protein (OX40L-FP) with a pox...

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Detalles Bibliográficos
Autores principales: Malamas, Anthony S., Hammond, Scott A., Schlom, Jeffrey, Hodge, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710887/
https://www.ncbi.nlm.nih.gov/pubmed/29207606
http://dx.doi.org/10.18632/oncotarget.19967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710887/
https://www.ncbi.nlm.nih.gov/pubmed/29207606
http://dx.doi.org/10.18632/oncotarget.19967

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