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PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer

PIK3CA mutations are frequent in gastric cancer. However, their pathological and clinical implications are still unclear. We analyzed the clinicopathological characteristics according to the PIK3CA mutation status of patients with stage IB–IV disease who underwent gastrectomy between May 2003 and De...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Won, Lee, Hye Seung, Nam, Kyung Han, Ahn, Soyeon, Kim, Jin Won, Ahn, Sang-Hoon, Park, Do Joong, Kim, Hyung-Ho, Lee, Keun-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710896/
https://www.ncbi.nlm.nih.gov/pubmed/29207615
http://dx.doi.org/10.18632/oncotarget.18770