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Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase in vitro and in vivo
Asparaginase has been reported to be effective in the treatment of various leukemia and several malignant solid cancers. However, the anti-tumor effect of asparaginase is always restricted due to complicated mechanisms. Herein, we investigated the mechanisms of how glioblastoma resisted asparaginase...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710905/ https://www.ncbi.nlm.nih.gov/pubmed/29207624 http://dx.doi.org/10.18632/oncotarget.19409 |