Cargando…

Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase in vitro and in vivo

Asparaginase has been reported to be effective in the treatment of various leukemia and several malignant solid cancers. However, the anti-tumor effect of asparaginase is always restricted due to complicated mechanisms. Herein, we investigated the mechanisms of how glioblastoma resisted asparaginase...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qicheng, Ye, Li, Fan, Jiajun, Zhang, Xuyao, Wang, Huan, Liao, Siyang, Song, Ping, Wang, Ziyu, Wang, Shaofei, Li, Yubin, Luan, Jingyun, Wang, Yichen, Chen, Wei, Zai, Wenjing, Yang, Ping, Cao, Zhonglian, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710905/
https://www.ncbi.nlm.nih.gov/pubmed/29207624
http://dx.doi.org/10.18632/oncotarget.19409