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CaMKII is involved in subcellular Ca(2+) redistribution-induced endoplasmic reticulum stress leading to apoptosis in primary cultures of rat proximal tubular cells exposed to lead

Lead (Pb) is a known nephrotoxic element. Recently we have proved that subcellular Ca(2+) redistribution is involved in Pb-induced apoptosis in primary cultures of rat proximal tubular (rPT) cells, but the underlying mechanism remains to be elucidated. Firstly, data showed that Pb triggers endoplasm...

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Detalles Bibliográficos
Autores principales: Wang, Min-Ge, Li, Wen-Hui, Wang, Xin-Yu, Yang, Du-Bao, Wang, Zhen-Yong, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710913/
https://www.ncbi.nlm.nih.gov/pubmed/29207633
http://dx.doi.org/10.18632/oncotarget.20035