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CaMKII is involved in subcellular Ca(2+) redistribution-induced endoplasmic reticulum stress leading to apoptosis in primary cultures of rat proximal tubular cells exposed to lead
Lead (Pb) is a known nephrotoxic element. Recently we have proved that subcellular Ca(2+) redistribution is involved in Pb-induced apoptosis in primary cultures of rat proximal tubular (rPT) cells, but the underlying mechanism remains to be elucidated. Firstly, data showed that Pb triggers endoplasm...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710913/ https://www.ncbi.nlm.nih.gov/pubmed/29207633 http://dx.doi.org/10.18632/oncotarget.20035 |