Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition

Wheat germ agglutinin (WGA) is a lectin that specifically binds cell surface glycoproteins and disrupts nuclear pore complex function through its interaction with POM121. Our data indicate WGA induces paraptosis-like cell death without caspase activation. We observed the main features of paraptosis,...

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Detalles Bibliográficos
Autores principales: Tsai, Tsung Lin, Wang, Hao Chen, Hung, Chun Hua, Lin, Peng Chan, Lee, Yi San, Chen, Helen H.W., Su, Wu Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710917/
https://www.ncbi.nlm.nih.gov/pubmed/29207637
http://dx.doi.org/10.18632/oncotarget.20436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710917/
https://www.ncbi.nlm.nih.gov/pubmed/29207637
http://dx.doi.org/10.18632/oncotarget.20436

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