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Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition
Wheat germ agglutinin (WGA) is a lectin that specifically binds cell surface glycoproteins and disrupts nuclear pore complex function through its interaction with POM121. Our data indicate WGA induces paraptosis-like cell death without caspase activation. We observed the main features of paraptosis,...
Autores principales: | Tsai, Tsung Lin, Wang, Hao Chen, Hung, Chun Hua, Lin, Peng Chan, Lee, Yi San, Chen, Helen H.W., Su, Wu Chou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710917/ https://www.ncbi.nlm.nih.gov/pubmed/29207637 http://dx.doi.org/10.18632/oncotarget.20436 |
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