Cargando…

Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca(2+)-mitochondria dependent pathway

Colorectal carcinoma (CRC) remains one of the leading causes of death in cancer-related diseases. In this study, we aimed to investigate the anticancer effect of Jolkinolide B (JB), a bioactive diterpenoid component isolated from the dried roots of Euphorbia fischeriana Steud, on CRC cells and its u...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jing, Wang, Yang, Zhou, Ye, He, Qing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710918/
https://www.ncbi.nlm.nih.gov/pubmed/29207638
http://dx.doi.org/10.18632/oncotarget.20077