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Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes

Recent studies have demonstrated that NLRP3 inflammasome complex acts as pivotal elements to initiate inflammatory responses and plays an important role in the dysfunction of cardiovascular complications. Meanwhile, simvastatin prevents vascular endothelial dysfunction from inflammasome invasion con...

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Detalles Bibliográficos
Autores principales: Lv, Zhen-Huan, Phuong, Trinh Anh, Jin, Shi-Jie, Li, Xiao-Xue, Xu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710924/
https://www.ncbi.nlm.nih.gov/pubmed/29207644
http://dx.doi.org/10.18632/oncotarget.20443