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Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3

Nitidine chloride (NC) is a natural alkaloid compound derived from the plant Zanthoxylum nitidum and is known for its therapeutic anticancer potential. In this study, we investigated the effects of NC on growth and signaling pathways in human oral cancer cell lines and a tumor xenograft model. The a...

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Detalles Bibliográficos
Autores principales: Kim, Lee-Han, Khadka, Sachita, Shin, Ji-Ae, Jung, Ji-Youn, Ryu, Mi-Heon, Yu, Hyun-Ju, Lee, Hae Nim, Jang, Boonsil, Yang, In-Hyoung, Won, Dong-Hoon, Kwon, Hye-Jeong, Jeong, Joseph H., Hong, Seong Doo, Cho, Nam-Pyo, Cho, Sung-Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710925/
https://www.ncbi.nlm.nih.gov/pubmed/29207645
http://dx.doi.org/10.18632/oncotarget.20444