Discovery of novel frizzled-7 inhibitors by targeting the receptor’s transmembrane domain

Frizzled (Fzd) proteins are seven transmembrane receptors that belong to a novel and separated family of G-protein-coupled receptors (GPCRs). The Fzd receptors can respond to Wnt proteins to activate the canonical β-catenin pathway which is important for both initiation and progression of cancers. D...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wei, Lu, Wenyan, Ananthan, Subramaniam, Suto, Mark J., Li, Yonghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710937/
https://www.ncbi.nlm.nih.gov/pubmed/29207657
http://dx.doi.org/10.18632/oncotarget.20665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710937/
https://www.ncbi.nlm.nih.gov/pubmed/29207657
http://dx.doi.org/10.18632/oncotarget.20665

Ejemplares similares