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Immunization with recombinant rabies virus expressing Interleukin-18 exhibits enhanced immunogenicity and protection in mice

Several studies have shown that interleukin-18 (IL-18) plays an important role in both innate and adaptive immune responses. In this study, we investigated the pathogenicity and immunogenicity of recombinant rabies virus expressing IL-18 (rHEP-IL18). Experimental results showed that Institute of Can...

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Detalles Bibliográficos
Autores principales: Gai, Weiwei, Zheng, Wenwen, Wang, Chong, Wong, Gary, Song, Yanyan, Zheng, Xuexing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710941/
https://www.ncbi.nlm.nih.gov/pubmed/29207661
http://dx.doi.org/10.18632/oncotarget.21065