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miR-15b represses BACE1 expression in sporadic Alzheimer’s disease

Beta-site Amyloid precursor protein Cleaving Enzyme 1 (BACE1) is conceived as a potential target for therapies against Alzheimer disease (AD). MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression in a sequence-specific manner. Although miRNAs have been increasingly r...

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Detalles Bibliográficos
Autores principales: Gong, Guohua, An, Fengmao, Wang, Yu, Bian, Ming, Yu, Li-Jun, Wei, Chengxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710945/
https://www.ncbi.nlm.nih.gov/pubmed/29207665
http://dx.doi.org/10.18632/oncotarget.21177