Genetic or pharmacologic inhibition of EGFR ameliorates sepsis-induced AKI

Despite recent studies have demonstrated that the EGF receptor (EGFR) activation provided a renoprotective role during ischemic and folic acid-induced AKI, the role and regulation mechanism of EGFR in septic AKI remains unclear. Here, gefitinib, a highly selective EGFR inhibitor, abrogated LPS-induc...

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Detalles Bibliográficos
Autores principales: Xu, Xuan, Wang, Juan, Yang, Ruhao, Dong, Zheng, Zhang, Dongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710948/
https://www.ncbi.nlm.nih.gov/pubmed/29207668
http://dx.doi.org/10.18632/oncotarget.21244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710948/
https://www.ncbi.nlm.nih.gov/pubmed/29207668
http://dx.doi.org/10.18632/oncotarget.21244

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