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Genetic or pharmacologic inhibition of EGFR ameliorates sepsis-induced AKI

Despite recent studies have demonstrated that the EGF receptor (EGFR) activation provided a renoprotective role during ischemic and folic acid-induced AKI, the role and regulation mechanism of EGFR in septic AKI remains unclear. Here, gefitinib, a highly selective EGFR inhibitor, abrogated LPS-induc...

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Detalles Bibliográficos
Autores principales:	Xu, Xuan, Wang, Juan, Yang, Ruhao, Dong, Zheng, Zhang, Dongshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710948/ https://www.ncbi.nlm.nih.gov/pubmed/29207668 http://dx.doi.org/10.18632/oncotarget.21244

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