Modulation of the prostaglandin-endoperoxide synthase 2 gene expression by variant haplotypes: influence of the 3′-untranslated region

The inducible inflammatory enzyme cycloxigenase-2 is up-regulated in cancer, and favors tumor progression. Cycloxigenase-2 is encoded by the prostaglandin-endoperoxide synthase 2 (PTGS2) gene, which presents sequence variations in the promoter region (PR) and in the 3′-untranslated region (3′-UTR)....

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Detalles Bibliográficos
Autores principales: Piranda, D.N., Abreu, R.B.V., Freitas-Alves, D.R., de Carvalho, M.A., Vianna-Jorge, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711006/
https://www.ncbi.nlm.nih.gov/pubmed/29211250
http://dx.doi.org/10.1590/1414-431X20176546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711006/
https://www.ncbi.nlm.nih.gov/pubmed/29211250
http://dx.doi.org/10.1590/1414-431X20176546

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