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Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains

An average mouse in midlife weighs between 25 and 30 g, with about a gram of tissue in the largest adipose depot (gonadal), and the weight of this depot differs between inbred strains. Specifically, C57BL/6ByJ mice have heavier gonadal depots on average than do 129P3/J mice. To understand the geneti...

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Detalles Bibliográficos
Autores principales: Lin, Cailu, Fesi, Brad D., Marquis, Michael, Bosak, Natalia P., Lysenko, Anna, Koshnevisan, Mohammed Amin, Duke, Fujiko F., Theodorides, Maria L., Nelson, Theodore M., McDaniel, Amanda H., Avigdor, Mauricio, Arayata, Charles J., Shaw, Lauren, Bachmanov, Alexander A., Reed, Danielle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711020/
https://www.ncbi.nlm.nih.gov/pubmed/29194435
http://dx.doi.org/10.1371/journal.pone.0188972