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Interleukin-1beta (IL-1β)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1β on human dystrophic myogenic cells

Duchenne muscular dystrophy (DMD) is a severe X-linked recessive muscle disorder caused by mutations in the dystrophin gene. Nonetheless, secondary processes involving perturbation of muscle regeneration probably exacerbate disease progression, resulting in the fatal loss of muscle in DMD patients....

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Detalles Bibliográficos
Autores principales: Nagata, Yuki, Kiyono, Tohru, Okamura, Kikuo, Goto, Yu-ichi, Matsuo, Masafumi, Ikemoto-Uezumi, Madoka, Hashimoto, Naohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711031/
https://www.ncbi.nlm.nih.gov/pubmed/29194448
http://dx.doi.org/10.1371/journal.pone.0188821