Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation

Quantitative relationship between the magnitude of variation in minor histocompatibility antigens (mHA) and graft versus host disease (GVHD) pathophysiology in stem cell transplant (SCT) donor-recipient pairs (DRP) is not established. In order to elucidate this relationship, whole exome sequencing (...

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Detalles Bibliográficos
Autores principales: Koparde, Vishal, Abdul Razzaq, Badar, Suntum, Tara, Sabo, Roy, Scalora, Allison, Serrano, Myrna, Jameson-Lee, Max, Hall, Charles, Kobulnicky, David, Sheth, Nihar, Feltz, Juliana, Contaifer, Daniel, Wijesinghe, Dayanjan, Reed, Jason, Roberts, Catherine, Qayyum, Rehan, Buck, Gregory, Neale, Michael, Toor, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711034/
https://www.ncbi.nlm.nih.gov/pubmed/29194460
http://dx.doi.org/10.1371/journal.pone.0187771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711034/
https://www.ncbi.nlm.nih.gov/pubmed/29194460
http://dx.doi.org/10.1371/journal.pone.0187771

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