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Cell cycle time series gene expression data encoded as cyclic attractors in Hopfield systems

Modern time series gene expression and other omics data sets have enabled unprecedented resolution of the dynamics of cellular processes such as cell cycle and response to pharmaceutical compounds. In anticipation of the proliferation of time series data sets in the near future, we use the Hopfield...

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Detalles Bibliográficos
Autores principales: Szedlak, Anthony, Sims, Spencer, Smith, Nicholas, Paternostro, Giovanni, Piermarocchi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711035/
https://www.ncbi.nlm.nih.gov/pubmed/29149186
http://dx.doi.org/10.1371/journal.pcbi.1005849