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Perturbation of the T cell receptor repertoire occurs with increasing age in dogs
Immunosenescence is the gradual deterioration in immune system function associated with ageing. This decline is partly due to involution of the thymus, which leads to a reduction in the output of naive T cells into the circulating lymphocyte pool. Expansion of existing naive and memory T cell popula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711257/ https://www.ncbi.nlm.nih.gov/pubmed/29103899 http://dx.doi.org/10.1016/j.dci.2017.10.020 |