Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations

Lipin-1 is a Mg(2+)-dependent phosphatidic acid phosphatase (PAP) that in mice is necessary for normal glycerolipid biosynthesis, controlling adipocyte metabolism, and adipogenic differentiation. Mice carrying inactivating mutations in the Lpin1 gene display the characteristic features of human fami...

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Detalles Bibliográficos
Autores principales: Pelosi, Michele, Testet, Eric, Le Lay, Soazig, Dugail, Isabelle, Tang, Xiaoyun, Mabilleau, Guillaume, Hamel, Yamina, Madrange, Marine, Blanc, Thomas, Odent, Thierry, McMullen, Todd P. W., Alfò, Marco, Brindley, David N., de Lonlay, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711497/
https://www.ncbi.nlm.nih.gov/pubmed/28986436
http://dx.doi.org/10.1194/jlr.P075440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711497/
https://www.ncbi.nlm.nih.gov/pubmed/28986436
http://dx.doi.org/10.1194/jlr.P075440

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