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High Concordance of a Closed-System, RT-qPCR Breast Cancer Assay for HER2 mRNA, Compared to Clinically Determined Immunohistochemistry, Fluorescence in situ Hybridization, and Quantitative Immunofluorescence

BACKGROUND: Historically, mRNA measurements have been tested on several commercially available platforms, but none have gained broad acceptance for assessment of HER2. An mRNA measurement, as a continuous value, has the potential for use in adjudication of the equivocal category. Here we use a real-...

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Detalles Bibliográficos
Autores principales: Wasserman, Brad E., Carvajal-Hausdorf, Daniel E., Ho, Kenneth, Wong, Wendy, Wu, Natalie, Chu, Victor C., Lai, Edwin W., Weidler, Jodi M., Bates, Michael, Neumeister, Veronique, Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711560/
https://www.ncbi.nlm.nih.gov/pubmed/28892092
http://dx.doi.org/10.1038/labinvest.2017.93