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High Concordance of a Closed-System, RT-qPCR Breast Cancer Assay for HER2 mRNA, Compared to Clinically Determined Immunohistochemistry, Fluorescence in situ Hybridization, and Quantitative Immunofluorescence
BACKGROUND: Historically, mRNA measurements have been tested on several commercially available platforms, but none have gained broad acceptance for assessment of HER2. An mRNA measurement, as a continuous value, has the potential for use in adjudication of the equivocal category. Here we use a real-...
Autores principales: | Wasserman, Brad E., Carvajal-Hausdorf, Daniel E., Ho, Kenneth, Wong, Wendy, Wu, Natalie, Chu, Victor C., Lai, Edwin W., Weidler, Jodi M., Bates, Michael, Neumeister, Veronique, Rimm, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711560/ https://www.ncbi.nlm.nih.gov/pubmed/28892092 http://dx.doi.org/10.1038/labinvest.2017.93 |
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