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Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Mast cells are implicated as detrimental players in inflammatory lung diseases, particularly asthma. Mast cells respond to activating stimuli by releasing a wide panel of pro-inflammatory compounds that can contribute profoundly to the pathology, and there is currently an unmet need for strategies t...

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Detalles Bibliográficos
Autores principales: Paivandy, Aida, Sandelin, Martin, Igelström, Helena, Landelius, Per, Janson, Christer, Melo, Fabio R., Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711769/
https://www.ncbi.nlm.nih.gov/pubmed/29230220
http://dx.doi.org/10.3389/fimmu.2017.01645