A Novel Function for the Streptococcus pneumoniae Aminopeptidase N: Inhibition of T Cell Effector Function through Regulation of TCR Signaling

Streptococcus pneumoniae (Spn) causes a variety of disease states including fatal bacterial pneumonia. Our previous finding that introduction of Spn into an animal with ongoing influenza virus infection resulted in a CD8(+) T cell population with reduced effector function gave rise to the possibilit...

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Detalles Bibliográficos
Autores principales: Blevins, Lance K., Parsonage, Derek, Oliver, Melissa B., Domzalski, Elizabeth, Swords, W. Edward, Alexander-Miller, Martha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711787/
https://www.ncbi.nlm.nih.gov/pubmed/29230212
http://dx.doi.org/10.3389/fimmu.2017.01610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711787/
https://www.ncbi.nlm.nih.gov/pubmed/29230212
http://dx.doi.org/10.3389/fimmu.2017.01610

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