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Single Dose of Consensus Hemagglutinin-Based Virus-Like Particles Vaccine Protects Chickens against Divergent H5 Subtype Influenza Viruses

The H5 subtype highly pathogenic avian influenza (HPAI) virus is one of the greatest threats to global poultry industry. To develop broadly protective H5 subunit vaccine, a recombinant consensus HA sequence (rHA) was constructed and expressed in virus-like particles (rHA VLPs) in the baculovirus-ins...

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Detalles Bibliográficos
Autores principales: Wu, Peipei, Lu, Jihu, Zhang, Xuehua, Mei, Mei, Feng, Lei, Peng, Daxin, Hou, Jibo, Kang, Sang-Moo, Liu, Xiufan, Tang, Yinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711813/
https://www.ncbi.nlm.nih.gov/pubmed/29230222
http://dx.doi.org/10.3389/fimmu.2017.01649