Neuroligin 2 R215H Mutant Mice Manifest Anxiety, Increased Prepulse Inhibition, and Impaired Spatial Learning and Memory

Neuroligin 2 (NLGN2) is a postsynaptic adhesion protein that plays an essential role in synaptogenesis and function of inhibitory neuron. We previously identified a missense mutation R215H of the NLGN2 in a patient with schizophrenia. This missense mutation was shown to be pathogenic in several cell...

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Detalles Bibliográficos
Autores principales: Chen, Chia-Hsiang, Lee, Pin-Wei, Liao, Hsiao-Mei, Chang, Pi-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711828/
https://www.ncbi.nlm.nih.gov/pubmed/29230184
http://dx.doi.org/10.3389/fpsyt.2017.00257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711828/
https://www.ncbi.nlm.nih.gov/pubmed/29230184
http://dx.doi.org/10.3389/fpsyt.2017.00257

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