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Lipoarabinomannan Decreases Galectin-9 Expression and Tumor Necrosis Factor Pathway in Macrophages Favoring Mycobacterium tuberculosis Intracellular Growth

Lipoarabinomannan (LAM) is a lipid virulent factor secreted by Mycobacterium tuberculosis (Mtb). LAM can be found in the sputum and urine of patients with active tuberculosis. When human monocytes are differentiated into macrophages [monocyte-derived macrophages (MDM)] in the presence of LAM, MDM ar...

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Detalles Bibliográficos
Autores principales: Chávez-Galán, Leslie, Ramon-Luing, Lucero, Carranza, Claudia, Garcia, Irene, Sada-Ovalle, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711832/
https://www.ncbi.nlm.nih.gov/pubmed/29230224
http://dx.doi.org/10.3389/fimmu.2017.01659