17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression

Estrogen replacement therapy increases the risk of human ovarian cancer and exogenous estradiol accelerates the onset of ovarian cancer in mouse models. This study uses primary cultures of mouse ovarian surface epithelium (OSE) to demonstrate that one possible mechanism by which estrogen accelerates...

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Detalles Bibliográficos
Autores principales: Vuong, Nhung H., Salah Salah, Omar, Vanderhyden, Barbara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711839/
https://www.ncbi.nlm.nih.gov/pubmed/29196616
http://dx.doi.org/10.1038/s41598-017-16219-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711839/
https://www.ncbi.nlm.nih.gov/pubmed/29196616
http://dx.doi.org/10.1038/s41598-017-16219-2

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