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17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression
Estrogen replacement therapy increases the risk of human ovarian cancer and exogenous estradiol accelerates the onset of ovarian cancer in mouse models. This study uses primary cultures of mouse ovarian surface epithelium (OSE) to demonstrate that one possible mechanism by which estrogen accelerates...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711839/ https://www.ncbi.nlm.nih.gov/pubmed/29196616 http://dx.doi.org/10.1038/s41598-017-16219-2 |