Toehold-enhanced LNA probes for selective pull down and single-molecule analysis of native chromatin

The organization of DNA into chromatin is thought to regulate gene expression in eukaryotes. To study its structure in vitro, there is a need for techniques that can isolate specific chromosomal loci of natively assembled chromatin. Current purification methods often involve chemical cross-linking t...

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Detalles Bibliográficos
Autores principales: Hermans, Nicolaas, Huisman, Juriën Jori, Brouwer, Thomas Bauke, Schächner, Christopher, van Heusden, G. Paul H., Griesenbeck, Joachim, van Noort, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711847/
https://www.ncbi.nlm.nih.gov/pubmed/29196662
http://dx.doi.org/10.1038/s41598-017-16864-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711847/
https://www.ncbi.nlm.nih.gov/pubmed/29196662
http://dx.doi.org/10.1038/s41598-017-16864-7

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