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Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
Inflammasomes are involved in gut homeostasis and inflammatory pathologies, but the role of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated periodic syndrome (CAPS) patients with NLRP3 mutations have autoinflammation in skin, joints, and eyes, but not in the intest...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711854/ https://www.ncbi.nlm.nih.gov/pubmed/29196621 http://dx.doi.org/10.1038/s41467-017-01917-2 |