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Addition of a histone deacetylase inhibitor increases recombinant protein expression in Medicago truncatula cell cultures

Plant cell cultures are an attractive platform for the production of recombinant proteins. A major drawback, hindering the establishment of plant cell suspensions as an industrial platform, is the low product yield obtained thus far. Histone acetylation is associated with increased transcription lev...

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Detalles Bibliográficos
Autores principales: Santos, Rita B., Pires, Ana Sofia, Abranches, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711867/
https://www.ncbi.nlm.nih.gov/pubmed/29196720
http://dx.doi.org/10.1038/s41598-017-17006-9