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Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β(1) and Shh Signalling
Diabetes is a risk factor for acute kidney injury (AKI) and chronic kidney disease (CKD). Diabetic patients are easy to progress to CKD after AKI. Currently, activation of fibrotic signalling including transforming growth factor-β(1) (TGF-β(1)) is recognized as a key mechanism in CKD. Here, we inves...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711892/ https://www.ncbi.nlm.nih.gov/pubmed/29196746 http://dx.doi.org/10.1038/s41598-017-16977-z |