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Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β(1) and Shh Signalling

Diabetes is a risk factor for acute kidney injury (AKI) and chronic kidney disease (CKD). Diabetic patients are easy to progress to CKD after AKI. Currently, activation of fibrotic signalling including transforming growth factor-β(1) (TGF-β(1)) is recognized as a key mechanism in CKD. Here, we inves...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Jin, Kang, Jun Mo, Park, Seon Hwa, Kwon, Hyuk-Kwon, Song, Seok-Jong, Moon, Haena, Kim, Su-Mi, Seo, Jung-Woo, Lee, Yu Ho, Kim, Yang Gyun, Moon, Ju-Young, Lee, So-Young, Son, Youngsook, Lee, Sang-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711892/
https://www.ncbi.nlm.nih.gov/pubmed/29196746
http://dx.doi.org/10.1038/s41598-017-16977-z