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Imaging viscosity of intragranular mucin matrix in cystic fibrosis cells

Abnormalities of mucus viscosity play a critical role in the pathogenesis of several respiratory diseases, including cystic fibrosis. Currently, there are no approaches to assess the rheological properties of mucin granule matrices in live cells. This is the first example of the use of a molecular r...

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Detalles Bibliográficos
Autores principales: Requena, Sebastian, Ponomarchuk, Olga, Castillo, Marlius, Rebik, Jonathan, Brochiero, Emmanuelle, Borejdo, Julian, Gryczynski, Ignacy, Dzyuba, Sergei V., Gryczynski, Zygmunt, Grygorczyk, Ryszard, Fudala, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711894/
https://www.ncbi.nlm.nih.gov/pubmed/29196739
http://dx.doi.org/10.1038/s41598-017-17037-2