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RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy

Dogs with X-linked hereditary nephropathy (XLHN) have a glomerular basement membrane defect that leads to progressive juvenile-onset renal failure. Their disease is analogous to Alport syndrome in humans, and they also serve as a good model of progressive chronic kidney disease (CKD). However, the g...

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Detalles Bibliográficos
Autores principales: Chu, Candice P., Hokamp, Jessica A., Cianciolo, Rachel E., Dabney, Alan R., Brinkmeyer-Langford, Candice, Lees, George E., Nabity, Mary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711945/
https://www.ncbi.nlm.nih.gov/pubmed/29196624
http://dx.doi.org/10.1038/s41598-017-16603-y