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Anti-idiotypic Antibodies against BP-IgG Prevent Type XVII Collagen Depletion

Bullous pemphigoid (BP) mainly targets type XVII collagen (COL17). Intravenous immunoglobulin (IVIg) is used to treat numerous autoimmune diseases, including BP. The major mechanism of action for IVIG is thought to be its immunomodulatory effect. However, little is known about the precise mechanisms...

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Detalles Bibliográficos
Autores principales: Kamaguchi, Mayumi, Iwata, Hiroaki, Mori, Yuiko, Toyonaga, Ellen, Ujiie, Hideyuki, Kitagawa, Yoshimasa, Shimizu, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712008/
https://www.ncbi.nlm.nih.gov/pubmed/29230227
http://dx.doi.org/10.3389/fimmu.2017.01669