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Fear Conditioning Downregulates Rac1 Activity in the Basolateral Amygdala Astrocytes to Facilitate the Formation of Fear Memory

Astrocytes are well known to scale synaptic structural and functional plasticity, while the role in learning and memory, such as conditioned fear memory, is poorly elucidated. Here, using pharmacological approach, we find that fluorocitrate (FC) significantly inhibits the acquisition of fear memory,...

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Detalles Bibliográficos
Autores principales: Liao, Zhaohui, Tao, Yezheng, Guo, Xiaomu, Cheng, Deqin, Wang, Feifei, Liu, Xing, Ma, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712045/
https://www.ncbi.nlm.nih.gov/pubmed/29230165
http://dx.doi.org/10.3389/fnmol.2017.00396