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Fear Conditioning Downregulates Rac1 Activity in the Basolateral Amygdala Astrocytes to Facilitate the Formation of Fear Memory
Astrocytes are well known to scale synaptic structural and functional plasticity, while the role in learning and memory, such as conditioned fear memory, is poorly elucidated. Here, using pharmacological approach, we find that fluorocitrate (FC) significantly inhibits the acquisition of fear memory,...
Autores principales: | Liao, Zhaohui, Tao, Yezheng, Guo, Xiaomu, Cheng, Deqin, Wang, Feifei, Liu, Xing, Ma, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712045/ https://www.ncbi.nlm.nih.gov/pubmed/29230165 http://dx.doi.org/10.3389/fnmol.2017.00396 |
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